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2500 BCE: Tarsus most likely develops from a trade center of the Hatti.
2334 BCE - 2083 BCE: Tarsus known as Tarsisi in the time of the Akkadian Empire.
1700 BCE - 1200 BCE: Tarsus known as Tarsa under the Hittites.
1276 BCE - 1178 BCE: Tarsus sacked by the Sea Peoples.
700 BCE - 612 BCE: Tarsus capital of Cilicia under Assyrians.
547 BCE - 333 BCE: Tarsus thrives under the Persian Empire.
400 BCE: Tarsus becomes the seat of a Persian Satrapy.
333 BCE: Stop over of Alexander the Great at Tarsus.
333 BCE: Tarsus taken by Alexander the Great.
103 BCE: Tarsus taken by Rome.
66 BCE: Populace of Tarsus receives Roman Citizenship.
64 BCE: Tarsus is capital of Roman Cilicia Campestris.
41 BCE: Cleopatra and Mark Antony meet at Tarsus.
27 BCE: Tarsus is capital of Roman province of Syria-Cilicia Phoenice.
27 BCE - 476 CE: Tarsus thrives under the Roman Empire.
5 CE: Paul the Apostle is born in Tarsus.
476 CE - 700 CE: Tarsus continues to flourish under Byzantine Empire.
700 CE - 965 CE: Tarsus taken by Muslim armies.
965 CE - 1453 CE: Tarsus is again under Byzantine control until the empire falls.
1453 CE: Tarsus is taken by the Ottoman Empire.